Aesthetic filler produce Kidney disease.
Polymethylmethacrylate, also known by its acronym PMMA is a plastic. In the medical world polymethylmethacrylate resin for the manufacture of bone and dental prosthesis. The use of polymethylmethacrylate (PMMA) as filler is approved by the FDA and ANMAT. In Argentina this substance is approved by ANMAT for Metacrill® brand. In the USA It is FDA approved for the product Artefill
PMMA microspheres are often used for filling facial depressions and grooves. Large amounts of PMMA began to be used as fillers in buttocks. This practice has resulted in serious complications such as pulmonary embolism Kills.
Recently a team of eminent Argentinian doctors has found that PMMA granulomas raises blood calcium levels and produce different degrees of renal insufficiency.